Case report<br>Cerebral amyloid angiopathy as a cause of an extensive brain hemorrhage in adult patient with Down’s syndrome  – a case report

Tadeusz Mendel; Ewa Bertrand; Grażyna M. Szpak; Tomasz Stępień; Teresa Wierzba-Bobrowicz

eISSN: 1509-572x
ISSN: 1641-4640

Folia Neuropathologica

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3/2010
vol. 48

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abstract:

Case report
Cerebral amyloid angiopathy as a cause of an extensive brain hemorrhage in adult patient with Down’s syndrome – a case report

Tadeusz Mendel

,

Ewa Bertrand

,

Grażyna M. Szpak

,

Tomasz Stępień

,

Teresa Wierzba-Bobrowicz

Folia Neuropathol 2010; 48 (3): 206-211

Online publish date: 2010/10/04

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A case of 54-year old woman who deceased due to consequence of extensive brain hemorrhage is presented. The patient was admitted to our Department of Neurology due to progressive quadriparesis as a complication of the cervical spinal cord compressive myelopathy. On the third day after neurosurgical decompression of the spinal cord sudden worsening of neurological and general condition was observed, finally caused death. An autopsy study revealed an extensive brain lobar hemorrhage and a dorsal-ventral compression of the cervical spinal cord. Alzheimer’s disease-type degenerative changes with concomitant CAA were seen in light microscope examination. Extensive foci of demyelination were found especially in dorsal funiculi of the cervical spinal cord. Smaller foci of demyelination were present in anterior funiculi due to the stenosis of vertebral canal.

keywords:

Case reportCerebral amyloid angiopathy as a cause of an extensive brain hemorrhage in adult patient with Down’s syndrome – a case report

Tadeusz Mendel , Ewa Bertrand , Grażyna M. Szpak , Tomasz Stępień , Teresa Wierzba-Bobrowicz

cerebral amyloid angiopathy, Down’s syndrome, brain hemorrhage, spinal cord compression

Case report
Cerebral amyloid angiopathy as a cause of an extensive brain hemorrhage in adult patient with Down’s syndrome – a case report

Tadeusz Mendel

,

Ewa Bertrand

,

Grażyna M. Szpak

,

Tomasz Stępień

,

Teresa Wierzba-Bobrowicz