Chordoid meningiomas of a different histopathological pattern. A report of two cases

Ewa Matyja; Wiesława Grajkowska; Marzena Łazarczyk; Michał Marchel; Tomasz Czernicki

eISSN: 1509-572x
ISSN: 1641-4640

Folia Neuropathologica

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1/2006
vol. 44

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abstract:

Chordoid meningiomas of a different histopathological pattern. A report of two cases

Ewa Matyja

,

Wiesława Grajkowska

,

Marzena Łazarczyk

,

Michał Marchel

,

Tomasz Czernicki

Folia Neuropathol 2006; 44 (1): 34-41

Online publish date: 2006/03/21

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Chordoid meningioma is an uncommon histopathological variant of meningioma with a peculiar chordoma-like appearance. Its association with systemic inflammatory disorder linked to Castleman’s syndrome was confirmed in the majority of young patients, however such a relationship in adults remains enigmatic. We report two cases of chordoid meningiomas in adult patients without manifestation of Castleman’s syndrome. One tumour was almost totally composed of chordoma-like areas whereas the second one exhibited the unique combination of chordoma- and chondroma-like pattern. This is the first description of chordoid meningioma combined with extensive cartilaginous metaplasia. Both tumours exhibited histological evidence of infiltrative growth, accompanied by a relatively high proliferative index within structures of chordoid appearance. The designation of the chordoid component in meningioma is very important as this subtype of meningioma exhibits a more aggressive biological behaviour and higher risk of recurrence.

keywords:

chordoid meningioma, cartilaginous metaplasia

Chordoid meningiomas of a different histopathological pattern. A report of two cases

Ewa Matyja , Wiesława Grajkowska , Marzena Łazarczyk , Michał Marchel , Tomasz Czernicki

chordoid meningioma, cartilaginous metaplasia

Ewa Matyja

,

Wiesława Grajkowska

,

Marzena Łazarczyk

,

Michał Marchel

,

Tomasz Czernicki