Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus

Paweł Reichert; Zdzisław Kiełbowicz; Piotr Dzięgiel; Bartosz Puła; Jan Kuryszko; Marcin Wrzosek; Maciej Kiełbowicz; Jerzy Gosk

doi:10.5114/fn.2015.56547

eISSN: 1509-572x
ISSN: 1641-4640

Folia Neuropathologica

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

4/2015
vol. 53

Send email

Copy url:

abstract:

Original paper

Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus

Paweł Reichert

,

Zdzisław Kiełbowicz

,

Piotr Dzięgiel

,

Bartosz Puła

,

Jan Kuryszko

,

Marcin Wrzosek

,

Maciej Kiełbowicz

,

Jerzy Gosk

Folia Neuropathol 2015; 53 (4): 327-342

DOI: https://doi.org/10.5114/fn.2015.56547

Online publish date: 2015/12/21

View full text Get citation

EndNote

Papers, Reference Manager, RefWorks, Zotero

AMA

Reichert P, Kiełbowicz Z, Dzięgiel P, et al. Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus. Folia Neuropathologica. 2015;53(4):327-342. doi:10.5114/fn.2015.56547.

APA

Reichert, P., Kiełbowicz, Z., Dzięgiel, P., Puła, B., Kuryszko, J.,  & Wrzosek, M. et al. (2015). Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus. Folia Neuropathologica, 53(4), 327-342. https://doi.org/10.5114/fn.2015.56547

Chicago

Reichert, Paweł, Zdzisław Kiełbowicz, Piotr Dzięgiel, Bartosz Puła, Jan Kuryszko, Marcin Wrzosek,  and Maciej Kiełbowicz et al. 2015. "Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus". Folia Neuropathologica 53 (4): 327-342. doi:10.5114/fn.2015.56547.

Harvard

Reichert, P., Kiełbowicz, Z., Dzięgiel, P., Puła, B., Kuryszko, J., Wrzosek, M., Kiełbowicz, M.,  and Gosk, J. (2015). Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus. Folia Neuropathologica, 53(4), pp.327-342. https://doi.org/10.5114/fn.2015.56547

MLA

Reichert, Paweł et al. "Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus." Folia Neuropathologica, vol. 53, no. 4, 2015, pp. 327-342. doi:10.5114/fn.2015.56547.

Vancouver

Reichert P, Kiełbowicz Z, Dzięgiel P, Puła B, Kuryszko J, Wrzosek M et al. Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus. Folia Neuropathologica. 2015;53(4):327-342. doi:10.5114/fn.2015.56547.

PlumX metrics:

Introduction: This study assessed the collateral sprouting in avulsion of the ventral branches of the C5 and C6 spinal nerves treated by coaptation of these nerves to the C7 spinal nerve on the brachial plexus of rabbits.

Material and methods: Thirty-six New Zealand rabbits were randomly divided into four groups: end-to-side coaptation (ESN) (n = 12), side-to-side coaptation (SSN) (n = 12), direct neurorrhaphy (end-to-end) (EEN) (n = 6) and no coaptation (n = 6). The operations were performed on the left brachial plexus. The contralateral, non-operated right brachial plexi were used as the control group. The groups were compared using morphological, electrophysiological and behavioral methods. The follow-up duration was 20 weeks.

Results: Significant differences were observed in all parameters when the experimental groups were compared with the control group and the no coaptation group. The histology of axonal regeneration after ESN, but not after SSN, was comparable to that after EEN. There were no significant differences in the electrophysiological, behavioral assessment or G-ratio parameters between the ESN and EEN groups. There were significant differences in the behavioral assessment, G-ratio and the histomorphometric parameters between the SSN and EEN groups, which disagreed with the electrophysiological results. Sensory axon collateral sprouting was more rapid than motor axon collateral sprouting.

Conclusions: The electrophysiological, histomorphometric and behavioral results obtained using end-to-side coaptation of ventral branches of the C5 and C6 spinal nerves to the C7 spinal nerve in the brachial plexi of rabbits confirm the occurrence of collateral sprouting at this level. After further research is performed to confirm the results of this study, end-to-side coaptation might emerge as an alternative method in the treatment of brachial plexus avulsion.

keywords:

Collateral sprouting axons of end-to-side nerve coaptation in the avulsion of ventral branches of the C5-C6 spinal nerves in the brachial plexus

Paweł Reichert , Zdzisław Kiełbowicz , Piotr Dzięgiel , Bartosz Puła , Jan Kuryszko , Marcin Wrzosek , Maciej Kiełbowicz , Jerzy Gosk

collateral sprouting, spinal nerves, brachial plexus, coaptation

Paweł Reichert

,

Zdzisław Kiełbowicz

,

Piotr Dzięgiel

,

Bartosz Puła

,

Jan Kuryszko

,

Marcin Wrzosek

,

Maciej Kiełbowicz

,

Jerzy Gosk