Dermatomyositis as a paraneoplastic syndrome of malignant melanoma or incidental coexistence?

Magdalena Krajewska; Hanna Bartosik; Wojciech Krajewski; Agnieszka Hałoń; Marian Klinger

doi:10.5114/dr.2016.61776

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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4/2016
vol. 103

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abstract:

Original paper

Dermatomyositis as a paraneoplastic syndrome of malignant melanoma or incidental coexistence?

Magdalena Krajewska

,

Hanna Bartosik

,

Wojciech Krajewski

,

Agnieszka Hałoń

,

Marian Klinger

Przegl Dermatol 2016, 103, 285–288

DOI: https://doi.org/10.5114/dr.2016.61776

Online publish date: 2016/09/01

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Introduction. Dermatomyositis is a rare systemic disease of connective tissue characterized by inflammation of the muscles and the skin. Malignant melanoma is a cancer that begins in melanocytes in the skin, mucosa of the rectum, intestine, oral cavity, external genitalia or in the eyeball.

Objective. Presentation of a patient with dermatomyositis as a possible paraneoplastic syndrome of malignant melanoma.

Case report. We present a case of a 56-year-old woman who was referred to us due to erythematous skin lesions on the limbs, face, neck and upper chest. The patient also complained of progressive muscle pain and weakness of the shoulder and pelvic girdle as well as of dysphagia. The patient had a small ulcerative lesion on the right foot that was removed. Histopathological evaluation revealed malignant melanoma cells, which were also present in the sentinel lymph node.

Conclusions. Screening in dermatomyositis patients should also be focused on melanoma, especially in cases with negative antibodies.

keywords:

Dermatomyositis as a paraneoplastic syndrome of malignant melanoma or incidental coexistence?

Magdalena Krajewska , Hanna Bartosik , Wojciech Krajewski , Agnieszka Hałoń , Marian Klinger

dermatomyositis, paraneoplastic syndrome, malignant melanoma

Magdalena Krajewska

,

Hanna Bartosik

,

Wojciech Krajewski

,

Agnieszka Hałoń

,

Marian Klinger