Diagnostic difficulties in a case of a female patient with pemphigus vulgaris

Maria Weryńska-Kalemba; Agata Filipowska-Grońska; Kamila Zawadzińska-Halat; Karolina Filipowska; Jerzy Jarząb

doi:10.5114/dr.2016.57743

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

1/2016
vol. 103

Send email

Copy url:

abstract:

Original paper

Diagnostic difficulties in a case of a female patient with pemphigus vulgaris

Maria Weryńska-Kalemba

,

Agata Filipowska-Grońska

,

Kamila Zawadzińska-Halat

,

Karolina Filipowska

,

Jerzy Jarząb

Przegl Dermatol 2016, 103, 52–55

DOI: https://doi.org/10.5114/dr.2016.57743

Online publish date: 2016/02/16

View full text Get citation

PlumX metrics:

Introduction. Autoimmune blistering diseases are mediated by autoantibodies directed against structural proteins of the skin. Pemphigus vulgaris (PV) is the most common type of pemphigus. The main auto-antigen in PV is desmoglein 3, although other antigens such as desmoglein 1, desmocollins, plakoglobin and pemphaxin may also be involved. More than 50% of cases begin with oral lesions. Skin lesions on the face appear occasionally.

Objective. To present an unusual clinical manifestation of pemphigus vulgaris.

Case report. We present a case of a 54-year-old female patient with skin lesions localized on the nose, who due to suspicion of skin cancer not confirmed by histopathology was referred to us by an oncologist. Pemphigus vulgaris was suspected when erosions on the oral mucosa were observed, and this diagnosis was established on the basis of immunological tests. The patient was treated with prednisone and azathioprine, with very good results.

Conclusions. We present the case owing to the difficulties in the diagnostic process and, moreover, due to spectacular clinical improvement after the treatment.

keywords:

Diagnostic difficulties in a case of a female patient with pemphigus vulgaris

Maria Weryńska-Kalemba , Agata Filipowska-Grońska , Kamila Zawadzińska-Halat , Karolina Filipowska , Jerzy Jarząb

basal cell carcinoma, pemphigus, autoimmune disease

Maria Weryńska-Kalemba

,

Agata Filipowska-Grońska

,

Kamila Zawadzińska-Halat

,

Karolina Filipowska

,

Jerzy Jarząb