EVALUATION OF CALCIUM HOMEOSTASIS IN PATIENTS TREATED IN TERNOPIL UNIVERSITY HOSPITAL FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Background. Osteoporosis is a significant problem in patients with advanced Chronic obstructive pulmonary disease. The etiology for the bone loss includes smoking, vitamin D deficiency,concomitant endocrine diseases, sedentary lifestyle, use of glucocorticoids. Osteoporosis is the pathology of calcium metabolism, thus the peculiarities of calcium homeostasis in Chronic obstructive pulmonary disease patients, depending on their bone mineral density were researched in the article.

Material and methods. It was examined 86 patients with stage 3 Chronic obstructive pulmonary disease. Bone densitometry was performed on lumbar vertebrae using dual energy X-ray absorption scanner “Lunar”.

Results. It was not find a significant difference in the duration of disease among patients suffering from 3rd stage CO PD with or without bone mass deficiency. All females with low bone mineral density had concomitant endocrine pathologies. It was established the increase of calcium content in sputum of patients with CO PD. Osteoporosis in patients with chronic obstructive pulmonary disease develops under influence of numerous factors, among which

are: lack of physical activity, increase in calcium excretion with urine and sputum, low amount of calcium in diet, reduced exposure to sunlight, concomitant endocrine diseases in females and exposure to stressful situations, smoking, vitamin D deficiency.

Conclusions. Osteoporosis in patients with chronic obstructive pulmonary disease develops under influence of numerous factors, among which are: lack of physical activity, increase in calcium excretion with urine and sputum, low amount of calcium in diet, reduced exposure to sunlight, concomitant endocrine diseases in females and exposure to stressful situations.