Effect of radiotherapy in a patient with Wegener’s granulomatosis – case report

Ewa Ziółkowska; Elżbieta Pietrusińska; Marta Biedka; Roman Makarewicz

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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9/2008
vol. 12

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abstract:

Effect of radiotherapy in a patient with Wegener’s granulomatosis – case report

Ewa Ziółkowska

,

Elżbieta Pietrusińska

,

Marta Biedka

,

Roman Makarewicz

Współczesna Onkologia (2008) vol. 12; 9 (406–409)

Online publish date: 2009/01/05

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Wegener’s granulomatosis is a systemic necrotizing vasculitis affecting small and medium sized vessels with associated granuloma formation. The onset of the disease is usually between 25 and 50 years of age, but it is becoming increasingly apparent that it can and does occur in childhood. Typically, the upper and lower respiratory tract and often the kidneys are involved. However, other organs including the skin, joints, heart, central nervous system, and eyes can also be affected. The clinical manifestations and symptoms are non-specific and include systemic findings such as fever, weight loss, arthralgia, and myalgia. Combined treatment with cytotoxic and corticosteroid agents has improved prognosis and long-term survival in patients with Wegener’s granulomatosis. The aim of this article is to present a patient with Wegener’s granuloma-tosis and discuss treatment methods, with special consideration of the role of radiotherapy.

keywords:

Effect of radiotherapy in a patient with Wegener’s granulomatosis – case report

Ewa Ziółkowska , Elżbieta Pietrusińska , Marta Biedka , Roman Makarewicz

Wegener’s granulomatosis, radiotherapy

Ewa Ziółkowska

,

Elżbieta Pietrusińska

,

Marta Biedka

,

Roman Makarewicz