eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Reviewers Abstracting and indexing Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
3/2018
vol. 15
 
Share:
Send email
Share:
abstract:
Original paper

Evaluation of the metabolic response to open and minimally invasive resection of the oesophagus due to oesophageal cancer

Jarosław Pieróg
,
Michał Bielewicz
,
Janusz Wójcik
,
Bartosz Kubisa
,
Krzysztof Kaseja
,
Krzysztof Safranow
,
Magdalena Dołęgowska
,
Piotr Waloszczyk
,
Tomasz Grodzki

Kardiochirurgia i Torakochirurgia Polska 2018; 15 (3): 151-156
DOI: https://doi.org/10.5114/kitp.2018.78438
Online publish date: 2018/09/24
View full text Get citation
 
PlumX metrics:
Aim
The aim of this study was to compare the metabolic response in the early postoperative period after radical resection of stage I and II oesophageal cancer applying a minimally invasive procedure and an open procedure involving classical laparotomy and thoracotomy.

Material and methods
Serum concentrations of interleukin 6 (IL-6), procalcitonin (PCT), C-reactive protein (CRP), tumour necrosis factor- (TNF-), and total serum protein (TP) and leukocyte count (WBC) in blood collected on the day of surgery prior to the procedure (day 0) and on days 1, 2 and 7 after the surgery were measured in two groups of patients undergoing oesophageal resection due to cancer: applying a minimally invasive procedure involving laparoscopy and videothoracoscopy (group A) and applying a classical procedure involving full opening of the chest and abdominal cavity (group B). The study involved a total of 24 patients divided into two groups of 12 patients each.

Results
Tumour necrosis factor- concentration was lower in group A compared to group B on day 0, PCT concentration was lower in group A compared to group B on day 2 after surgery, and on the remaining days TNF- and PCT concentrations were not statistically different between groups.

Conclusions
Lower concentration of PCT on post-surgery day 2 in the group of patients undergoing minimally invasive oesophageal resection seems to be associated with a smaller perioperative injury. Lower TNF- concentration in serum collected on day 0 in the group of patients undergoing minimally invasive resection is associated with a lower stage of oesophageal cancer in this group.

keywords:

minimally invasive resection of oesophagus, oeso-phageal cancer, metabolic response
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.