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Alergologia Polska - Polish Journal of Allergology
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1/2018
vol. 5
 
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abstract:
Guidelines/recommendations

Hypersensitivity to drugs and substances used during anaesthesia. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology

Joanna Glück
,
Grażyna Bochenek
,
Anna Bodzenta-Łukaszyk
,
Marek L. Kowalski
,
Joanna Makowska
,
Marita Nittner-Marszalska
,
Grzegorz Porębski
,
Grażyna Sławeta
,
Barbara Rymarczyk

Alergologia Polska – Polish Journal of Allergology 2018; 5, 1: 38–44
DOI: https://doi.org/10.5114/pja.2018.74447
Online publish date: 2018/03/23
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Hypersensitivity reactions to drugs used in general anesthesia are responsible for 9–19% complications of anesthetic procedures. Identification of culprit drug is difficult because typically several drugs from different pharmacological classes are used at the short time and because of limited possibility of obtaining of anamnestic data from a patient. Hypersensitivity may be caused by different pathomechanisms. Skin tests are the main diagnostic procedure and only in exceptional cases provocations are performed. Apart from drugs other factors such as latex, volume replacement therapy and antiseptics such as chlorhexidine should be taking into consideration.
keywords:

anesthetics, neuromuscular agents, hypnotics, general anesthesia


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