Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology

Joanna Makowska; Grażyna Bochenek; Joanna Glück; Marita Nittner-Marszalska; Grzegorz Porębski; Barbara Rymarczyk; Grażyna Sławeta; Marek L. Kowalski

doi:10.5114/pja.2018.74444

eISSN: 2391-6052
ISSN: 2353-3854

Alergologia Polska - Polish Journal of Allergology

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abstract:

Guidelines/recommendations

Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology

Joanna Makowska

,

Grażyna Bochenek

,

Joanna Glück

,

Marita Nittner-Marszalska

,

Grzegorz Porębski

,

Barbara Rymarczyk

,

Grażyna Sławeta

,

Marek L. Kowalski

Alergologia Polska – Polish Journal of Allergology 2018; 5, 1: 10–22

DOI: https://doi.org/10.5114/pja.2018.74444

Online publish date: 2018/03/23

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AMA

Makowska J, Bochenek G, Glück J, et al. Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology. Alergologia Polska - Polish Journal of Allergology. 2018;5(1):10-22. doi:10.5114/pja.2018.74444.

APA

Makowska, J., Bochenek, G., Glück, J., Nittner-Marszalska, M., Porębski, G.,  & Rymarczyk, B. et al. (2018). Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology. Alergologia Polska - Polish Journal of Allergology, 5(1), 10-22. https://doi.org/10.5114/pja.2018.74444

Chicago

Makowska, Joanna, Grażyna Bochenek, Joanna Glück, Marita Nittner-Marszalska, Grzegorz Porębski, Barbara Rymarczyk,  and Grażyna Sławeta et al. 2018. "Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology". Alergologia Polska - Polish Journal of Allergology 5 (1): 10-22. doi:10.5114/pja.2018.74444.

Harvard

Makowska, J., Bochenek, G., Glück, J., Nittner-Marszalska, M., Porębski, G., Rymarczyk, B., Sławeta, G.,  and Kowalski, M. (2018). Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology. Alergologia Polska - Polish Journal of Allergology, 5(1), pp.10-22. https://doi.org/10.5114/pja.2018.74444

MLA

Makowska, Joanna et al. "Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology." Alergologia Polska - Polish Journal of Allergology, vol. 5, no. 1, 2018, pp. 10-22. doi:10.5114/pja.2018.74444.

Vancouver

Makowska J, Bochenek G, Glück J, Nittner-Marszalska M, Porębski G, Rymarczyk B et al. Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology. Alergologia Polska - Polish Journal of Allergology. 2018;5(1):10-22. doi:10.5114/pja.2018.74444.

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Non-steroidal anti-inflammatory drugs are the second after antibiotics group of drugs being the cause of drug hypersensitivity. The most common symptoms of nonsteroidal anti-inflammatory drugs (NSAIDs) hypersensitivity include cutaneous reactions with urticaria and angioedema and respiratory reactions (NSAIDs Exacerbated Respiratory Disease). Because in most of the cases the NSAIDs hypersensitivity is caused by non-immunological reaction due to cyclooxygenase-1 inhibition, the detailed history confirmed by challenge testing play crucial role in the diagnostics. In most of the cases reactions are evoked by the drugs having potency to inhibit cyclooxygenase-1 while drugs inhibiting specifically cyclooxygenase-2 are generally well tolerated.

keywords:

Hypersensitivity to nonsteroidal anti-inflammatory drugs. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology

Joanna Makowska , Grażyna Bochenek , Joanna Glück , Marita Nittner-Marszalska , Grzegorz Porębski , Barbara Rymarczyk , Grażyna Sławeta , Marek L. Kowalski

nonsteroidal anti-inflammatory drugs, cyclooxygenase, hypersensitivity

Joanna Makowska

,

Grażyna Bochenek

,

Joanna Glück

,

Marita Nittner-Marszalska

,

Grzegorz Porębski

,

Barbara Rymarczyk

,

Grażyna Sławeta

,

Marek L. Kowalski