Isomorphic response in a case of quinolone-induced acute generalized exanthematous pustulosis

Konchok Dorjay; Soumya Sachdeva; Surabhi Sinha

doi:10.5114/dr.2020.101673

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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5/2020
vol. 107

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abstract:

Case report

Isomorphic response in a case of quinolone-induced acute generalized exanthematous pustulosis

Konchok Dorjay

¹

,

Soumya Sachdeva

¹

,

Surabhi Sinha

¹

Dr. Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, India

Dermatol Rev/Przegl Dermatol 2020, 107, 454-458

DOI: https://doi.org/10.5114/dr.2020.101673

Online publish date: 2020/12/29

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Acute generalized exanthematous pustulosis is a severe, life-threatening, drug-induced cutaneous eruption that is associated with appearance of non-follicular sterile pustules on an erythematous base usually with oedema. We report a case of acute generalized exanthematous pustulosis induced by ofloxacin given for acute diarrhea. The patient was then treated successfully with oral glucocorticosteroids. However, what was notable was that he developed linear non-follicular pustules on the back indicating an isomorphic response (Koebner phenomenon) in acute generalized exanthematous pustulosis, which has not been reported before in the published English literature.

keywords:

Isomorphic response in a case of quinolone-induced acute generalized exanthematous pustulosis

Konchok Dorjay 1 , Soumya Sachdeva 1 , Surabhi Sinha 1

acute generalized exanthematous pustulosis, quinolone, isomorphic response, Koebner phenomenon

Konchok Dorjay

¹

,

Soumya Sachdeva

¹

,

Surabhi Sinha

¹