KARDIOCHIRURGIA DOROSŁYCH<br>Is C-reactive protein level before cardiac operations  for the most common indications helpful in risk prediction of in-hospital postoperative complications?

Mirosław Bitner; Sławomir Jander; Andrzej Walczak; Karol Bartczak; Małgorzata Misztal; Bogdan Jegier; Ryszard Jaszewski

eISSN: 1897-4252
ISSN: 1731-5530

Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery

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1/2009
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abstract:

KARDIOCHIRURGIA DOROSŁYCH
Is C-reactive protein level before cardiac operations for the most common indications helpful in risk prediction of in-hospital postoperative complications?

Mirosław Bitner

,

Sławomir Jander

,

Andrzej Walczak

,

Karol Bartczak

,

Małgorzata Misztal

,

Bogdan Jegier

,

Ryszard Jaszewski

Kardiochirurgia i Torakochirurgia Polska 2009; 6 (1): 11–16

Online publish date: 2009/03/31

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AMA

Bitner M, Jander S, Walczak A, et al. KARDIOCHIRURGIA DOROSŁYCHIs C-reactive protein level before cardiac operations  for the most common indications helpful in risk prediction of in-hospital postoperative complications?. Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery. 2009;6(1):11-16.

APA

Bitner, M., Jander, S., Walczak, A., Bartczak, K., Misztal, M.,  & Jegier, B. et al. (2009). KARDIOCHIRURGIA DOROSŁYCHIs C-reactive protein level before cardiac operations  for the most common indications helpful in risk prediction of in-hospital postoperative complications?. Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery, 6(1), 11-16.

Chicago

Bitner, Mirosław, Sławomir Jander, Andrzej Walczak, Karol Bartczak, Małgorzata Misztal, Bogdan Jegier,  and Ryszard Jaszewski. 2009. "KARDIOCHIRURGIA DOROSŁYCHIs C-reactive protein level before cardiac operations  for the most common indications helpful in risk prediction of in-hospital postoperative complications?". Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery 6 (1): 11-16.

Harvard

Bitner, M., Jander, S., Walczak, A., Bartczak, K., Misztal, M., Jegier, B.,  and Jaszewski, R. (2009). KARDIOCHIRURGIA DOROSŁYCHIs C-reactive protein level before cardiac operations  for the most common indications helpful in risk prediction of in-hospital postoperative complications?. Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery, 6(1), pp.11-16.

MLA

Bitner, Mirosław et al. "KARDIOCHIRURGIA DOROSŁYCHIs C-reactive protein level before cardiac operations  for the most common indications helpful in risk prediction of in-hospital postoperative complications?." Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery, vol. 6, no. 1, 2009, pp. 11-16.

Vancouver

Bitner M, Jander S, Walczak A, Bartczak K, Misztal M, Jegier B et al. KARDIOCHIRURGIA DOROSŁYCHIs C-reactive protein level before cardiac operations  for the most common indications helpful in risk prediction of in-hospital postoperative complications?. Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery. 2009;6(1):11-16.

Background: Studies on this topic use different CRP cut-off values and their results are divergent.
Aim: To answer the question: can preoperative CRP>5 mg/L predict either atrial fibrillation, or other complications in patients who underwent heart operation?

Material and Methods: 85 patients underwent operations: 59 for CAD (51 on, 8 off-pump), and 26 for valve diseases (aged from 21 to 78 years, 61 male, 24 female). 39 (45.8%) had increased CRP level (range: 6.7-131.2; 24.97±24.71 mg/L on average), and 46 (54.2%) had normal (range: 0-4.5; 1.78±1.11 mg/L on average; p<0.001).
Age, gender, preoperative EF and CRP, maximal CKMB, and WBC with neutrophil percentage at discharge were compared in two pairs of contrary groups: with/without complications, and with paroxysmal AF/sinus rhythm. Receiver operating characteristic (ROC) curves were drawn for both pairs of groups.

Results: Patients with complications were significantly older, and had significantly higher CKMB, whereas other parameters in these groups, as in all AF/sinus rhythm ones, did not differ. The ROC curves confirmed that preoperative CRP level does not discriminate between patients and there is no sense in looking for a cut-off point.

Conclusions: Increased preoperative CRP value cannot be a predictor of complicated early outcome after heart surgery. Better cut-off CRP predictive value cannot be found. Complications, except for AF, were depended on higher age, and myocardial injury represented by increased postoperative CKMB level. Despite a lack of statistical evidence, a delay of elective operations should possibly be considered in patients with very high CRP level.

keywords:

KARDIOCHIRURGIA DOROSŁYCHIs C-reactive protein level before cardiac operations for the most common indications helpful in risk prediction of in-hospital postoperative complications?

Mirosław Bitner , Sławomir Jander , Andrzej Walczak , Karol Bartczak , Małgorzata Misztal , Bogdan Jegier , Ryszard Jaszewski

C-reactive protein, heart surgery, atrial fibrillation, postoperative complications

KARDIOCHIRURGIA DOROSŁYCH
Is C-reactive protein level before cardiac operations for the most common indications helpful in risk prediction of in-hospital postoperative complications?

Mirosław Bitner

,

Sławomir Jander

,

Andrzej Walczak

,

Karol Bartczak

,

Małgorzata Misztal

,

Bogdan Jegier

,

Ryszard Jaszewski