Late onset non-familiar acrokeratosis verruciformis of Hopf

Michelle Alcocer-Salas; Mary Santiago-Benitez; José Zepeda-Torres

doi:10.5114/dr.2022.123986

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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4/2022
vol. 109

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abstract:

Case report

Late onset non-familiar acrokeratosis verruciformis of Hopf

Michelle Alcocer-Salas

¹

,

Mary Jose Santiago-Benitez

²

,

José Maria Zepeda-Torres

³

Department of Dermatology, Instituto Dermatológico de Jalisco “Dr. José Barba Rubio”, Jalisco, Mexico
Medica Sur, Departament of Internal Medicine, Ciudad de Mexico, Mexico
Department of Mentoring, Universidad Autónoma de Guadalajara, Guadalajara, Mexico

Dermatol Rev/Przegl Dermatol 2022, 109, 310-315

DOI: https://doi.org/10.5114/dr.2022.123986

Online publish date: 2023/01/16

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Introduction
Hopf’s verruciform acrokeratosis is a genodermatosis characterized by keratotic lesions on the dorsa of the hands and feet. It usually develops during childhood but can occasionally develop at later ages, even in the fifth decade.

Case Report
We present the case of a 34-year-old man with phototype IV, who presented with cutaneous lesions that affected the forearms and hands on the dorsal surface, with a tendency to symmetry, consisting of multiple skin-coloured keratotic papules and erythematous lesions, of different sizes, some with a tendency to converge, rough surface with well- defined edges. The lesions were characterized by a chronic evolution.

Conclusions
Because of its low prevalence, there are still no treatment guidelines, however topical or oral retinoid treatment, as well as laser and cryotherapy, are useful. The disease is prone to recurrence.

keywords:

Late onset non-familiar acrokeratosis verruciformis of Hopf

Michelle Alcocer-Salas 1 , Mary Jose Santiago-Benitez 2 , José Maria Zepeda-Torres 3

dermatology, dermatosis, skin diseases

Michelle Alcocer-Salas

¹

,

Mary Jose Santiago-Benitez

²

,

José Maria Zepeda-Torres

³