eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications
2/2024
vol. 20
 
Share:
Send email
Share:
abstract:
Original paper

Left main coronary artery disease treated with beating heart surgery: 10-year single center results

Tomasz K. Urbanowicz
1
,
Michał Michalak
2
,
Anna Olasińska-Wiśniewska
1
,
Marcel Żukowski
3
,
Kamil Koczorowski
3
,
Bartosz Łasowski
3
,
Michał Woźnicki
3
,
Krzysztof J. Filipiak
4
,
Andrzej Tykarski
4
,
Marek Jemielity
1

  1. Cardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, Poznan, Poland
  2. Department of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland
  3. Poznan University of Medical Sciences, Poznan, Poland
  4. Department of Hypertensiology, Angiology and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
Adv Interv Cardiol 2024; 20, 2 (76): 157–163
DOI: https://doi.org/10.5114/aic.2024.140319
Online publish date: 2024/06/06
View full text Get citation
 
Introduction:
Left main (LM) coronary disease is believed to represent a complex, advanced, and potentially life-threatening atherosclerotic syndrome that can be treated by either percutaneous or surgical interventions. Despite its satisfactory results, the declined number of off-pump coronary artery bypass grafting (OPCAB) is observed.

Aim:
To compare 10-year survival and point out possible mortality risk factors in patients referred for left main and multivessel OPCAB surgery followed by transit time bypass measurements.

Material and methods:
There were 159 patients (128 (81%) men and 31 (19%) women) in a median age of 66 (60–70) years enrolled in retrospective analysis who were referred to surgical intervention due to left main (51, 32%) and multivessel (108, 68%) disease. The regression analysis for long-term mortality risk and the Kaplan-Meyer survival curve were analyzed.

Results:
Multivariable analysis pointed female sex (HR = 1.08, 95% CI: 1.03–1.14, p = 0.001) and diabetes mellitus (HR = 6.33, 95% CI: 1.86–21.52, p = 0.003) as possible risk factors for 10-year mortality risk. There was no significant difference in Kaplan-Meyer 10-year mortality comparison between left main and multivessel disease patients treated by off-pump surgical revascularization (HR = 0.93, 95% CI: 0.40–2.13, p = 0.86).

Conclusions:
Off-pump surgery in the left main disease, compared to multivessel disease, represents a safe surgical technique with satisfactory long-term results. The female sex and diabetes mellitus were found as possible risk factors for 10-year mortality risk in multivariable analysis.

keywords:

antiplatelet therapy, atrial fibrillation, stroke prevention, left atrial appendage closure, device-related thrombus
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.