eISSN: 2081-2841
ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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1/2017
vol. 9
 
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abstract:
Case report

Locally advanced adenocarcinoma of the cervix on uterus didelphys: a case report

Abel Cordoba
,
Alexandre Escande
,
Pauline Comte
,
Ingrid Fumagalli
,
Lucie Bresson
,
Ndaye Mubiayi
,
Eric Lartigau

J Contemp Brachytherapy 2017; 9, 1: 71–76
Online publish date: 2017/01/31
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In November 2013, a woman with Herlyn-Werner-Wunderlich (HWW) syndrome was diagnosed with a locally advanced left cervical adenocarcinoma. The patient’s malformation consisted of two uteri with two cervixes, a obstructed vagina, and a left renal agenesis. Classification FIGO: stage IIIa because of infiltration of the inferior third of the vagina wall. Locoregional management comprised an infrarenal lateral aortic lymphadenectomy followed by concomitant radio-chemotherapy to the pelvic (inguinal, pelvic, and infrarenal para aortic nodes) volumes. A total of 50.4 Gy were delivered (1.8 Gy/fraction/day) to the node (inguinal, pelvic, and aortic infrarenal) and pelvic volume; a concomitant boost to the primary cervical tumor and macroscopic nodes to 59.92 Gy (2.14 Gy/fraction/day) was performed. 20 Gy were delivered with intracavitary brachytherapy boost with mold technique and a pulsed-dose-rate technique due to the rarity of this uterine malformation. After 30 months of follow-up, there was no evidence of locoregional or distant recurrence.
keywords:

cervix cancer, cervical cancer, pulsed-dose-rate, uterus didelphys

 
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