Long-term survival of stage Ib lung adenocarcinoma with postoperative brain oligometastasis: a case report and literature review

Kai Xu; Xing Feng; Limin Wang; Quan Du; Er Jin

doi:10.5114/fn.2023.131120

eISSN: 1509-572x
ISSN: 1641-4640

Folia Neuropathologica

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

1/2024
vol. 62

Send email

Copy url:

abstract:

Case report

Long-term survival of stage Ib lung adenocarcinoma with postoperative brain oligometastasis: a case report and literature review

Kai Xu

¹

,

Xing Feng

²

,

Limin Wang

¹

,

Quan Du

³

,

Er Jin

¹

Department of Respiratory Medicine, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, China
Department of Thoracic Surgery, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, China
Department of Brain Surgery, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, China

Folia Neuropathol 2024; 62 (1): 108-112

DOI: https://doi.org/10.5114/fn.2023.131120

Online publish date: 2023/09/08

View full text Get citation

PlumX metrics:

Lung adenocarcinoma remains one of the most frequent and deadly tumour entities. Early-stage lung adenocarcinoma is extremely difficult to detect and is also easy to recur or metastasize after treatment. Since the new adenocarcinoma classification was presented in 2011, several studies have shown that patients with solid and/or micropapillary (S/MP) predominant patterns showed a worse prognosis. Here we report the case of a 54-year-old woman who was diagnosed with stage Ib lung adenocarcinoma with S/MP components and developed an isolated brain oligometastasis after resection and adjuvant therapy. A craniocerebral operation was performed, combined with radiotherapy and targeted therapy, and the patient eventually achieved a good quality of life. Our work reviews the clinical features of lung cancer complicated with S/MP components, the relationship between MP and epidermal growth factor receptor (EGFR) mutation, as well as treatment strategies for such a patient with postoperative brain oligometastasis of lung adenocarcinoma complicated with EGFR Exon19del mutation.

keywords:

Long-term survival of stage Ib lung adenocarcinoma with postoperative brain oligometastasis: a case report and literature review

Kai Xu 1 , Xing Feng 2 , Limin Wang 1 , Quan Du 3 , Er Jin 1

stage Ib lung adenocarcinoma, EGFR mutation, brain oligometastasis, micropapillary and solid

Kai Xu

¹

,

Xing Feng

²

,

Limin Wang

¹

,

Quan Du

³

,

Er Jin

¹