Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction

Ozluk O, Yılmaz M, Topal D, et al. Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction. Central European Journal of Immunology. 2016;41(4):386-391. doi:10.5114/ceji.2016.65138.

APA

Ozluk, O., Yılmaz, M., Topal, D., Tenekecioglu, E., Peker, T.,  & Kanat, S. et al. (2016). Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction. Central European Journal of Immunology, 41(4), 386-391. https://doi.org/10.5114/ceji.2016.65138

Chicago

Ozluk, Ozlem Arican, Mustafa Yılmaz, Dursun Topal, Erhan Tenekecioglu, Tezcan Peker, Selcuk Kanat,  and Kemal Karaagac et al. 2016. "Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction". Central European Journal of Immunology 41 (4): 386-391. doi:10.5114/ceji.2016.65138.

Harvard

Ozluk, O., Yılmaz, M., Topal, D., Tenekecioglu, E., Peker, T., Kanat, S., Karaagac, K., Vatansever, F.,  and Parlak, U. (2016). Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction. Central European Journal of Immunology, 41(4), pp.386-391. https://doi.org/10.5114/ceji.2016.65138

MLA

Ozluk, Ozlem Arican et al. "Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction." Central European Journal of Immunology, vol. 41, no. 4, 2016, pp. 386-391. doi:10.5114/ceji.2016.65138.

Vancouver

Ozluk O, Yılmaz M, Topal D, Tenekecioglu E, Peker T, Kanat S et al. Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction. Central European Journal of Immunology. 2016;41(4):386-391. doi:10.5114/ceji.2016.65138.

PlumX metrics:

Introduction: Neutrophil to lymphocyte ratio (NLR) was revaled to have a close relation with atherosclerotic cardiovascular disease. The relationship between NLR and culprit plaque localization has never been studied.

Aim of the study: To evaluate the association between NLR and unstable plaque localization of left anterior descending artery (LAD) in anterior miyocardial infarction patients.

Material and methods: Patients admitted to our hospital with acute anterior STEMI were included. Fifhy-eight patients who have single-vessel disease at LAD and their hematological parameters were analyzed retrospectively. Proximal segment of LAD lesions were groupped as Group I and mid segment of the LAD lesion groupped as Group II. The groups were compared according to their NLR and other parameters.

Results: Between group I (n = 41, mean age 52.5 ±12.7) and group II (n = 17, mean ages 52.0 ±10.8); NLR, were significantly higher in group I compared to the group II (6.9 ±5.6 vs. 3.3 ±2.0, p = 0.01). In group I, left ventricular ejection fraction (LVEF) was significantly lower (p = 0.02). In correlation analyzes, NLR was positively correlated with CK MB (r = 0.32, p = 0.01) and negatively correlated with LVEF (r = –0.28, p = 0.03).

Conclusions: The present study demonstrated that anterior myocardial infarction patients with high NLR had a greater possibility having proximal culprit lesion on the LAD. Therefore NLR can be used as a useful tool to culprit plaque localization in patients with acute miyocardial infarction patients.

keywords:

Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction

Ozlem Arican Ozluk , Mustafa Yılmaz , Dursun Topal , Erhan Tenekecioglu , Tezcan Peker , Selcuk Kanat , Kemal Karaagac , Fahriye Vatansever , Utku Parlak

coronary artery disease, neutrophil to lymphocyte ratio, acute coronary syndrome

Ozlem Arican Ozluk

,

Mustafa Yılmaz

,

Dursun Topal

,

Erhan Tenekecioglu

,

Tezcan Peker

,

Selcuk Kanat

,

Kemal Karaagac

,

Fahriye Vatansever

,

Utku Parlak