Pancreatic cystic lesions in diabetes mellitus patients

Martyna Rozek; Michal Lipinski; Ewa Jozefik; Zuzanna Znajdek; Marta Kiziak; Marta Sznurkowska; Jacek Tatur; Malgorzata Degowska; Grazyna Rydzewska

doi:10.5114/pg.2020.96080

eISSN: 1897-4317
ISSN: 1895-5770

Gastroenterology Review/Przegląd Gastroenterologiczny

Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

1/2021
vol. 16

Send email

Copy url:

abstract:

Original paper

Pancreatic cystic lesions in diabetes mellitus patients

Martyna Rozek

¹

,

Michal Lipinski

¹

,

Ewa Jozefik

¹

,

Zuzanna Znajdek

¹

,

Marta Kiziak

¹

,

Marta Sznurkowska

¹

,

Jacek Tatur

¹

,

Malgorzata Degowska

¹

,

Grazyna Rydzewska

^{1, 2}

Department of Gastroenterology, Central Clinical Hospital of the Ministry of Interior, Warsaw, Poland
Collegium Medicum, Jan Kochanowski Universuty, Kielce, Poland

Gastroenterology Rev 2021; 16 (1): 62–66

DOI: https://doi.org/10.5114/pg.2020.96080

Online publish date: 2020/06/04

View full text Get citation

PlumX metrics:

Introduction
According to the literature exocrine pancreatic insufficiency is relatively common among patients with diabetes mellitus (DM). Pseudocysts are the most common cystic lesions and may be formed in the setting of acute or chronic pancreatitis. However, whether DM is involved or not in pancreatic cyst formation is still not well established.

Aim
To investigate the frequency and risk factors of cystic lesions in diabetic patients.

Material and methods
One hundred and sixty-one patients with DM, with no previous history of pancreatic diseases, were prospectively included in the study. Endosonography followed by fine needle aspiration biopsy was then performed.

Results
Finally, 33 of 161 patients (20.5%) were recognized with cystic lesions of the pancreas. Among them 5 patients were classified as cystic neoplasms, and 28 as pseudocysts. In the group of patients with pseudocysts, cystic lesions were significantly more prevalent in individuals with DM lasting less than 3 years. Prevalence of cystic lesions was significantly higher in metformin users in comparison to other diabetic patients (p < 0.05). Cystic lesions were more frequent in patients above 50 years of age (p < 0.05).

Conclusions
The prevalence of cystic lesions in the diabetic population is higher than in the general population. DM seems to play a major role in the process of cyst development, especially in patients without previous history of pancreatitis. Higher prevalence of cystic lesions in early diabetes seems to be the first stage of pancreatic injury. The exact role of diabetes duration and type of treatment should be established.

keywords:

Pancreatic cystic lesions in diabetes mellitus patients

Martyna Rozek 1 , Michal Lipinski 1 , Ewa Jozefik 1 , Zuzanna Znajdek 1 , Marta Kiziak 1 , Marta Sznurkowska 1 , Jacek Tatur 1 , Malgorzata Degowska 1 , Grazyna Rydzewska 1, 2

diabetes mellitus, pancreatic pseudocyst, endosonography

Martyna Rozek

¹

,

Michal Lipinski

¹

,

Ewa Jozefik

¹

,

Zuzanna Znajdek

¹

,

Marta Kiziak

¹

,

Marta Sznurkowska

¹

,

Jacek Tatur

¹

,

Malgorzata Degowska

¹

,

Grazyna Rydzewska

^{1, 2}