Paraneoplastic urticaria in the course of gastric cancer

Paulina Rutecka; Dawid Wolak; Karolina Piskorowska; Bogna Migacz-Michalecka; Iwona Gisterek-Grocholska

doi:10.5114/dr.2024.146749

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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4/2024
vol. 111

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abstract:

Case report

Paraneoplastic urticaria in the course of gastric cancer

Paulina Rutecka

¹

,

Dawid Wolak

¹

,

Karolina Piskorowska

¹

,

Bogna Migacz-Michalecka

¹

,

Iwona Gisterek-Grocholska

¹

Department of Oncology and Radiotherapy, Medical University of Silesia, Katowice, Poland

Dermatol Rev/Przegl Dermatol 2024, 111, 305-308

DOI: https://doi.org/10.5114/dr.2024.146749

Online publish date: 2025/01/17

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Introduction:
Paraneoplastic syndromes are clinical manifestations associated with cancer which are not a direct consequence of malignancies. Chronic spontaneous urticaria is characterized by recurrent whealing of the skin for at least 6 weeks with ambiguous etiopathogenesis.

Objective:
We present a very rare case of the paraneoplastic syndrome in the form of urticaria in gastric cancer.

Case report:
A 61-year-old patient presented to the physician because of urticaria occurring at nights in various locations. An irregular ulceration was detected in the gastric body; being diagnosed as gastric cancer. The patient received 4 cycles of preoperative chemotherapy with the FLOT regimen, followed by a subtotal distal gastrectomy (Billroth II), and 4 cycles of postoperative chemotherapy. After that, the urticaria resolved.

Conclusions:
The described clinical situation shows a clear association between the occurrence of chronic urticaria and gastric cancer. No description of a similar clinical case was found in the available literature.

keywords:

Paraneoplastic urticaria in the course of gastric cancer

Paulina Rutecka 1 , Dawid Wolak 1 , Karolina Piskorowska 1 , Bogna Migacz-Michalecka 1 , Iwona Gisterek-Grocholska 1

paraneoplastic syndrome, urticaria, pruritus, stomach neoplasm

Paulina Rutecka

¹

,

Dawid Wolak

¹

,

Karolina Piskorowska

¹

,

Bogna Migacz-Michalecka

¹

,

Iwona Gisterek-Grocholska

¹