Preliminary data concerning methodology of assessment of serum autoantibodies not included into CTS-s diagnostic criteria

Jakub Ząbek; Agnieszka Palacz; Iwona Krzewska; Joanna Pyka; Sławomir Maśliński

eISSN: 2084-9834
ISSN: 0034-6233

Reumatologia/Rheumatology

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6/2006
vol. 44

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abstract:

Preliminary data concerning methodology of assessment of serum autoantibodies not included into CTS-s diagnostic criteria

Jakub Ząbek

,

Agnieszka Palacz

,

Iwona Krzewska

,

Joanna Pyka

,

Sławomir Maśliński

Reumatologia 2006; 44, 6: 293–297

Online publish date: 2006/12/15

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Authors are presenting preliminary data introducing a new way of complex analysis of the sera (ANA-positive but without estimated certain specificity), using for the neutralization and removing of “masking” (competing) antibodies (in the test ANA-Hep-2) a full bovine and spleen soluble protein extracts/called ENA, followed by further analysis of the antibody specificities present in neutralized sera by specific ELISA or Western-blott tests dependently on the basic pattern of ANA in the serum.

keywords:

connective tissue diseases, “marker” autoantibody, so called “auxiliary” autoantibodies, “serological diagnostic methods”

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Preliminary data concerning methodology of assessment of serum autoantibodies not included into CTS-s diagnostic criteria

Jakub Ząbek , Agnieszka Palacz , Iwona Krzewska , Joanna Pyka , Sławomir Maśliński

connective tissue diseases, “marker” autoantibody, so called “auxiliary” autoantibodies, “serological diagnostic methods”

Jakub Ząbek

,

Agnieszka Palacz

,

Iwona Krzewska

,

Joanna Pyka

,

Sławomir Maśliński