Primary amelanotic melanoma of the nail bed

Aleksandra Rosiak-Buller; Anna Płaszczyńska; Martyna Sławińska; Joanna Lakomy; Michał Sobjanek

doi:10.5114/dr.2021.110805

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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4/2021
vol. 108

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abstract:

Case report

Primary amelanotic melanoma of the nail bed

Aleksandra Rosiak-Buller

¹

,

Anna Płaszczyńska

²

,

Martyna Sławińska

²

,

Joanna Lakomy

³

,

Michał Sobjanek

²

Dermatology Ward, Voivodship Hospital, Plock, Poland
Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland
Department of Pathomorphology, Medical University of Gdansk, Gdansk, Poland

Dermatol Rev/Przegl Dermatol 2021, 108, 290-298

DOI: https://doi.org/10.5114/dr.2021.110805

Online publish date: 2021/12/13

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Introduction
Melanoma of the nail apparatus is rare in the Caucasian population and accounts for less than 1% of all diagnosed cases of melanoma. It most often derives from melanocytes of the nail unit matrix, while the bed of the nail is rarely the starting point.

Objective
Melanoma of the nail apparatus is rare in the Caucasian population and accounts for less than 1% of all diagnosed cases of melanoma. It most often derives from melanocytes of the nail unit matrix, while the bed of the nail is rarely the starting point.

Case report
We present a 64-year-old man with a history of immunosuppressive treatment because of pemphigus vulgaris. The patient developed a tumor of the nail bed of the left first toe. The nail plate was removed under regional anesthesia, revealing a pigment-free tumor of the nail bed, which was excised. Nail apparatus melanoma was diagnosed on the basis of the histopathological examination.

Conclusions
The presented case and the analysis of literature data prove the necessity of histopathological verification of each pathological mass occupying the bed of the nail unit.

keywords:

Primary amelanotic melanoma of the nail bed

Aleksandra Rosiak-Buller 1 , Anna Płaszczyńska 2 , Martyna Sławińska 2 , Joanna Lakomy 3 , Michał Sobjanek 2

nail apparatus melanoma, amelanotic melanoma, acral melanoma, subungal tumor

Aleksandra Rosiak-Buller

¹

,

Anna Płaszczyńska

²

,

Martyna Sławińska

²

,

Joanna Lakomy

³

,

Michał Sobjanek

²