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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
Bieżący numer Archiwum Artykuły zaakceptowane O czasopiśmie Zeszyty specjalne Rada naukowa Bazy indeksacyjne Prenumerata Kontakt Zasady publikacji prac Standardy etyczne i procedury
Panel Redakcyjny
Zgłaszanie i recenzowanie prac online
SCImago Journal & Country Rank
6/2023
vol. 110
 
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Artykuł specjalny

Primary cutaneous lymphomas. Diagnostic and therapeutic guidelines of the Polish Dermatological Society (PTD) and Polish Lymphoma Research Group (PLRG)

Małgorzata Sokołowska-Wojdyło
1, 2
,
Berenika Olszewska
1, 2
,
Ewa Chmielowska
2, 3, 4
,
Ewa Robak
5
,
Monika Prochorec-Sobieszek
6, 7
,
Grażyna Kamińska-Winciorek
8
,
Joanna Maj
9
,
Anna Kowalczyk
10
,
Adam Reich
11
,
Aleksandra Lesiak
12, 13
,
Joanna Narbutt
12
,
Jacek Szepietowski
9
,
Anna Jolanta Woźniacka
5
,
Agnieszka Barbara Owczarczyk-Saczonek
14
,
Joanna Romejko-Jarosińska
15
,
Agnieszka Giza
2, 16
,
Roman J. Nowicki
1
,
Andrzej Kazimierz Jaworek
16
,
Jan Maciej Zaucha
2, 17

  1. Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
  2. Polish Lymphoma Research Group (PLRG)
  3. Oncology Center, Bydgoszcz, Poland
  4. Specialist Oncology Hospital, Tomaszów Mazowiecki, Poland
  5. Department of Dermatology and Venereology, Medical University of Lodz, Lodz, Poland
  6. Department of Cancer Pathomorphology, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland
  7. Department of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
  8. Department of Bone Marrow Transplantation and Hematology-Oncology, Maria Skłodowska-Curie National Research Institute
  9. Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland
  10. Department of Oncology and Radiotherapy, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
  11. Department of Dermatology, Institute of Medical Sciences, College of Medical Sciences, University of Rzeszów, Rzeszow, Poland
  12. Department of Dermatology, Paediatric and Oncologic Dermatology, Medical University of Lodz, Lodz, Poland
  13. Laboratory of Autoinflammatory, Genetic and Rare Skin Disorders, Medical University of Lodz, Lodz, Poland
  14. Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, University of Warmia and Mazury, Olsztyn, Poland
  15. Department of Lymphoid Malignancies, Maria Sk³odowska-Curie Institute of Oncology, Warsaw, Poland
  16. Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland
  17. Department of Hematology and Transplantology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Dermatol Rev/Przegl Dermatol 2023, 110, 647-674
Data publikacji online: 2024/05/03
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Primary cutaneous lymphomas are a heterogeneous group of rare lymphoproliferative diseases that are initially limited to the skin but potentially also involve the lymph nodes, blood, and occasionally visceral organs. They develop from mature T cells, B cells, and NK cells. The classification includes a wide range of pathologies, each characterized by distinct clinical symptoms and variations in disease course. Cutaneous lymphomas are typically chronic in nature, and a complete cure is rarely achievable. Since primary cutaneous lymphomas are uncommon and present in many variants, they pose diagnostic and therapeutic challenges that require multidisciplinary collaboration between dermatologists, pathologists, hematologists, and oncologists. We present revised guidelines for the diagnosis and treatment of primary cutaneous lymphomas, with the goal of simplifying the diagnostic and therapeutic procedure in routine clinical practice. The guidelines cover the clinical, histopathological, and dermoscopic characteristics of skin lesions, along with recommendations for the diagnostic and therapeutic management of primary cutaneous lymphomas. When selecting the most suitable therapeutic approach for individual patients diagnosed with primary cutaneous lymphoma, the main factor to consider should be the clinical stage of the disease. However, other factors, such as the patient’s age, overall health, and medical history, should also be taken into account. The choice of therapy should be guided by finding optimal efficacy and safety. The guidelines also include globally recognized therapeutic approaches that are currently not accessible in Poland. The recommendations rely on the existing Polish and global guidelines, and the knowledge and experience of experts.


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