Psoriatic arthritis – classification, diagnostic and clinical aspects

Paweł Chabros; Aldona Pietrzak; Jacek Gągała; Grzegorz Kandzierski; Dorota Krasowska

doi:10.5114/dr.2020.93969

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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1/2020
vol. 107

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abstract:

Review paper

Psoriatic arthritis – classification, diagnostic and clinical aspects

Paweł Chabros

¹

,

Aldona Pietrzak

²

,

Jacek Gągała

¹

,

Grzegorz Kandzierski

³

,

Dorota Krasowska

²

Clinic of Orthopaedics and Traumatology, Orthopaedics Department, Medical University of Lublin, Lublin, Poland/Klinika Ortopedii i Traumatologii, Katedra Ortopedii, Uniwersytet Medyczny w Lublinie, Lublin, Polska
Department of Dermatology, Venereology, and Paediatric Dermatology, Medical University of Lublin, Lublin, Poland/Katedra i Klinika Dermatologii, Wenerologii i Dermatologii Dziecięcej, Uniwersytet Medyczny w Lublinie, Lublin, Polska
Orthopaedics and Peadiatric Rehabilitation Department,Univeristy Children's Hospital, Medical University of Lublin, Lublin, Poland/Klinika Ortopedii i Rehabilitacji Dziecięcej, Uniwersytecki Szpital Dziecięcy, Uniwersytet Medyczny w Lublinie, Lublin, Polska

Dermatol Rev/Przegl Dermatol 2020, 107, 32-43

DOI: https://doi.org/10.5114/dr.2020.93969

Online publish date: 2020/03/30

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From 5% to 40% patients with psoriatic skin lesions develop psoriatic arthritis, but 15% to 30% of patients with psoriasis suffer from undiagnosed psoriatic arthritis. The key role in development o-f psoriasis is played by T-lymphocytes and release of proinflammatory cytokines, interferon and adhesive proteins. Infection may exert an influence on psoriasis vulgaris and psoriatic arthritis development. The presence of antibodies against the antigens of Yersinia spp., Campylobacter spp. and Chlamydia trachomatis was more frequently observed in the serum of patients with psoriatic arthritis. Diagnosis of psoriatic arthritis may be based on CASPAR criteria. Diagnostic imaging (CT, MRI, USG) are routine diagnostic procedures in psoriatic arthritis. Several sub-types of psoriatic arthritis have been identified. Questionnaires to identify early stages of the disease have been constructed. Genetic factors, cigarette smoking, alcohol abuse, infections, stress and environmental factors may affect clinical course and results of treatment of psoriasis vulgaris and psoriatic arthritis. In severe cases, the disease may lead to disability.

keywords:

Psoriatic arthritis – classification, diagnostic and clinical aspects

Paweł Chabros 1 , Aldona Pietrzak 2 , Jacek Gągała 1 , Grzegorz Kandzierski 3 , Dorota Krasowska 2

psoriasis, psoriatic arthritis, T-lymphocytes, proinflammatory cytokines, diagnosis, therapeutics

Paweł Chabros

¹

,

Aldona Pietrzak

²

,

Jacek Gągała

¹

,

Grzegorz Kandzierski

³

,

Dorota Krasowska

²