eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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3/2022
vol. 18
 
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abstract:
Original paper

Quality of life after percutaneous paravalvular leak closure – a prospective registry

Michal Kozlowski
1
,
Magdalena Malczewska
2
,
Piotr Pysz
3
,
Marek Jędrzejek
1
,
Wojciech Wojakowski
1
,
Grzegorz Smolka
1

  1. Department of Cardiology and Structural Heart Diseases, Upper Silesian Medical Center, Katowice, Poland
  2. 2nd Department of Cardiology, Upper Silesian Medical Center, Katowice, Poland
  3. Cardiac Rehabilitation Department Treatment and Rehabilitation Center, Long-Term Care Hospital, Jaworze, Poland
Adv Interv Cardiol 2022; 18, 3 (69): 261–268
DOI: https://doi.org/10.5114/aic.2022.120451
Online publish date: 2022/10/19
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Introduction
Presence of paravalvular leaks (PVLs) can lead to heart failure, which decreases quality of life (QoL). Percutaneous closure is becoming the first-line treatment of PVLs, but whether such a procedure could improve QoL in these patients has never been examined. Aim: To examine changes in scores of the Minnesota Living with Heart Failure Questionnaire (MLHFQ) and Kansas City Cardiomyopathy Questionnaire (KCCQ) after percutaneous PVL closure.

Material and methods
Forty subjects with heart failure symptoms and at least moderate PVL were included in this prospective registry. QoL was assessed at baseline and during a 12-month follow-up after percutaneous PVL closure by MLHFQ and KCCQ questionnaires. Changes in NT-proBNP and lactate dehydrogenase (LDH) levels were also analyzed.

Results
Technical success (TS) was achieved in 97.5% of cases and procedural success (PS) in 85% of cases. In the group with PS a significant decrease in MLHFQ score as well as an increase in scores of all KCCQ domains was observed. No statistically significant changes were observed in the group without PS, mainly due to the small sample size.

Conclusions
Percutaneous PVL closure is associated with better QoL during a 12-month follow-up provided PS was achieved. Due to the low number of subjects in whom PS was not achieved, it is not possible to determine the influence of a failed procedure in this group of patients.

keywords:

paravalvular leak, quality of life, structural heart diseases, heart failure
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