eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications
6/2024
vol. 41
 
Share:
Send email
Share:
abstract:
Original paper

Relationship between cigarette smoking and chronic spontaneous urticaria. Is there a difference in neutrophil-lymphocyte ratio?

Łukasz Moos
1
,
Weronika Chodak
2
,
Magdalena Czyczerska
2
,
Karolina Garbino
2
,
Oktawia Gleba
2
,
Bartosz Śnietka
2
,
Zenon Brzoza
1

  1. Department of Internal Medicine, Allergology, Endocrinology and Gastroenterology, University Hospital in Opole, Opole, Poland
  2. Students Scientific Association “Alergos”, Faculty of Medicine, University of Opole, Department of Internal Medicine, Allergology, Endocrinology and Gastroenterology, University Hospital, Opole, Poland
Adv Dermatol Allergol 2024; XLI (6): 617–621
DOI: https://doi.org/10.5114/ada.2024.143640
Online publish date: 2024/09/30
View full text Get citation
 
Introduction:
Chronic spontaneous urticaria (CSU) is defined as the appearance of itchy wheals and/or angioedema for at least 6 weeks. Cigarette smoking is one of the world’s most common addictions. It is a cause of serious diseases such as renal cancer or thromboembolic incidents. Nevertheless, some studies show that nicotine might have a protective effect on various autoimmune diseases. The neutrophil-lymphocyte ratio (NLR) is a good marker of inflammation.

Aim:
To check the prevalence of smokers in our CSU patients and to assess their profile of NLR as a marker of inflammation.

Material and methods:
68 adult patients were included (52 females, and 16 males). The average age of respondents was 52. All of the patients were diagnosed with CSU. The group was divided by gender and smoking. The Mann-Whitney U test (Statistica ver.13) was used.

Results:
73.5% of the respondents were non-smokers, and the remaining 26.5% were smokers. In the female group, irrespective of smoking, statistically significant different levels of neutrophils (NEU), lymphocytes (LYM), and neutrophil-lymphocyte ratio (NLR) were found compared to males. No statistical difference was found between smokers and non-smokers regarding the level of inflammatory factors. Compared to males, females had significantly different levels of LYM in the group of non-smokers and NEU in the group of smokers.

Conclusions:
Our study does not support claims that smoking has a protective effect on CSU. Significant differences in NEU, LYM, and NLR need to be further investigated.

keywords:

urticaria, spontaneous urticaria, smoking, cigarettes, neutrophil-lymphocyte ratio
FEATURED PRODUCTS
BOOKS
• Atopowe Zapalenie Skóry • Choroby alergiczne w praktyce lekarza rodzinnego • Alergologia – kompendium
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.