Role of selected adipokines in psoriasis

Anna Baran; Iwona Flisiak; Bożena Chodynicka

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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5/2011
vol. 98

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abstract:

Review paper

Role of selected adipokines in psoriasis

Anna Baran

,

Iwona Flisiak

,

Bożena Chodynicka

Przegl Dermatol 2011, 98, 422–428

Online publish date: 2011/11/14

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Psoriasis is a chronic and recurrent skin disease, affecting 1.5-3% of the population. It is characterized by abnormal epidermal proliferation, immunological disturbances with predominance of Th1 response and complex pathogenesis. There are correlations between psoriasis and obesity, cardiovascular diseases, diabetes and metabolic syndrome. Adipokines, bioactive substances secreted by adipose tissue, exert a variety of metabolic activities and are associated with many diseases. In the article the possible role of adipokines in psoriasis is evaluated.

keywords:

Role of selected adipokines in psoriasis

Anna Baran , Iwona Flisiak , Bożena Chodynicka

psoriasis, resistin, chemerin, wisfatin, retinol binding protein-4

Anna Baran

,

Iwona Flisiak

,

Bożena Chodynicka