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Alergologia Polska - Polish Journal of Allergology
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3/2023
vol. 10
 
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abstract:
Special paper

Safety of performing selected allergological procedures in drug hypersensitivity. Position of the Drug Hypersensitivity Section of the Polish Society of Allergology

Grażyna Bochenek
1
,
Marta Chełmińska
2
,
Joanna Gluck
3
,
Marita Nittner-Marszalska
4
,
Grzegorz Porębski
5
,
Aleksandra Wardzyńska
6

  1. Klinika Pulmonologii, II Katedra Chorób Wewnętrznych im. Prof. A. Szczeklika, Uniwersytet Jagielloński Collegium Medicum, Kraków, Polska
  2. Klinika Alergologii, Katedra Pneumonologii i Alergologii, Gdański Uniwersytet Medyczny, Gdańsk, Polska
  3. Katedra i Klinika Chorób Wewnętrznych, Alergologii i Immunologii Klinicznej, Śląski Uniwersytet Medyczny, Katowice, Polska
  4. Klinika Chorób Wewnętrznych, Pneumonologii i Alergologii, Uniwersytet Medyczny, Wrocław, Polska
  5. Zakład Alergologii Klinicznej i Środowiskowej, Uniwersytet Jagielloński Collegium Medicum, Kraków, Polska
  6. Klinika Immunologii i Alergii, Uniwersytet Medyczny w Łodzi, Łódź, Polska
Alergologia Polska – Polish Journal of Allergology 2023; 10, 3: 152–166
DOI: https://doi.org/10.5114/pja.2023.131704
Online publish date: 2023/09/30
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Diagnostic and therapeutic procedures performed in patients with a history of drug hypersensitivity reactions involve controlled exposure to the causative factor and therefore carry the risk of inducing hypersensitivity symptoms. This document presents the necessary requirements to ensure the safety of these procedures. It describes skin prick tests, intradermal and patch tests, drug provocations, including provocations with acetylsalicylic acid, and drug desensitization. The evaluation of individual procedures distinguishes patients at high and ordinary risk, takes into account indications and contraindications and specific situations such as pregnancy, mastocytosis, the use of β-blockers and ACEIs. Recommendations refer to the equipment and place of performing a given procedure, the time of observation after its completion and the qualifications of the medical staff.
keywords:

drug allergy, safety, desensitization, diagnosis, drug hypersensitivity reactions, drug provocation tests, skin tests


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