Solitary extramedullary plasmocytoma of the skin

Introduction. Multiple myeloma is a monoclonal gammopathy characterized by uncontrolled proliferation of B lymphocytes and overproduction of immunoglobulins. The main symptoms are: bone destruction, anemia, blood hyperviscosity, hypercalcemia and renal changes. Extramedullary myeloma (plasmocytoma) is very rare.

Objective. Presentation of a case of myeloma involving only the skin.

Case report. We present a 50-year old man with a neoplastic lesion localized in the occipital region. The patient was admitted to our department with recurrence in the place of a previous primary lesion removed 2 years ago. In haematological and biochemical tests and in imaging investigations no relevant abnormalities or other occult neoplastic infiltration were detected. He was treated with surgical removal of the tumor and radiotherapy. Up to January 2015 no new lesions or signs of systemic involvement were observed.

Conclusions. The patient should undergo very regular checkup, because the course of solitary extramedullary plasmocytoma of the skin is more aggressive than other forms of multiple myeloma.