Study on the relationship between 25-hydroxyvitamin D level and rehabilitation of stroke patients

Aim of the study
To analyse the relationship between 25-hydroxyvitamin D (25(OH)D) level and rehabilitation in stroke patients.

Material and methods
100 stroke patients hospitalized in the Neurorehabilitation Department of China Rehabilitation Research Center from November 2019 to April 2020 were selected as the research subjects. And set up a case group. 50 subjects who underwent outpatient physical examination in China Rehabilitation Research Center in the same period were selected as the control group. The differences of biochemical and bone metabolism indexes such as serum 25(OH)D, blood lipid, liver and kidney function between the two groups were analysed. We took rehabilitation efficacy as the dependent variable, Pearson correlation analysis and multivariate logistic regression analysis were performed to analyse the indicators affecting rehabilitation efficacy.

Results
The average level of 25(OH)D in the case group was significantly lower than that in the control group (p < 0.05). The rehabilitation efficacy was significantly positively correlated with 25(OH)D level (p < 0.003) and significantly negatively correlated with duration of disease (p < 0.01) and NIHSS score (p < 0.05).

Conclusions
The increase in 25(OH)D is a protective factor for non-occurrence of cerebral infarction, and the increase in the 25(OH)D level is conducive to the prognosis of cerebral infarction.