eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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3/2012
vol. 9
 
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abstract:

TORAKOCHIRURGIA
Spindle cell neoplastic and non-neoplastic lesions of the pleura

Małgorzata Szołkowska
,
Renata Langfort
,
Barbara Burakowska
,
Ewa Szczepulska-Wójcik
,
Beata Maksymiuk
,
Piotr Rudziński
,
Tadeusz Orłowski

Kardiochirurgia i Torakochirurgia Polska 2012; 3: 340–351
DOI: https://doi.org/10.5114/kitp.2012.30847
Online publish date: 2012/10/01
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Pleural lesions composed of spindle fibroblast-like cells embedded in collagenous stroma comprise both neoplastic and reactive diseases. The differential diagnosis includes such common entities as chronic fibrous pleuritis and pleural plaques, less frequent ones such as solitary fibrous tumour, and such rare ones as desmoplastic malignant mesothelioma, calcifying tumour and desmoid tumour. The diagnosis, not easy in a postoperative specimen, is particularly difficult in small biopsy material. Clinical and radiological correlation as well as immunohistochemical reactions are needed and are often essential to establish the final diagnosis.

Detailed differentiation of rare spindle cell pleural lesions in microscopic analysis, immunohistochemistry, clinical course and radiological examination is described in this article.
keywords:

mesothelioma, spindle cell lesion, pleura, immunohistochemistry
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