Diagnostic difficulties in drug adverse reactions

Dorota Jenerowicz

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

5/2005
vol. 22

Send email

Copy url:

abstract:

Diagnostic difficulties in drug adverse reactions

Dorota Jenerowicz

PDiA 2005; XXII, 5: 233–238

Online publish date: 2005/10/28

View full text Get citation

In the paper authors present contemporary literature data regarding diagnostic procedures in drug hypersensitivity – a significant problem, being a matter of intense research for many years. Indications for use, the method and also scientific spectrum of skin tests, main in vitro investigations and provocation tests with culprit drugs have been described. Undoubtfully diagnostic difficulties result from enormous heterogeneity of clinical picture and etiopathogenesis of drug adverse reactions and they are also caused by individual procedures\' imperfections. One of the controversies considers required time interval between adverse drug reaction and the diagnostic approach, which depends on the type of drug hypersensitivity and also the method used and ranges from 3 weeks to 20 years.

keywords:

Diagnostic difficulties in drug adverse reactions

Dorota Jenerowicz

maculo-papular exanthem, lymphocyte transformation test, beta-lactam antibiotics