eISSN: 1509-572x
ISSN: 1641-4640
Folia Neuropathologica
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4/2021
vol. 59
 
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abstract:
Review paper

Underlying causes of cerebral palsy: public health perspectives

Gulnara Kapanova
1
,
Shynar Malik
1
,
Aima Adylova
2

  1. Al Farabi Kazakh National University, Kazakhstan
  2. Kazakhstan School of Public Health, Kazakhstan
Folia Neuropathol 2021; 59 (4): 386-392
Online publish date: 2021/12/30
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Cerebral palsy (CP) is a neurological pathology that is characterized by a combination of signs and symptoms that occur in neurodegenerative or metabolic disorder during the first few years of life. It is a complex pathology orchestrated by a plethora of different causes. The current diagnostic regimen for CP involves brain magnetic resonance imaging (MRI), and antenatal and perinatal insult. Despite advances in the field of genetics and molecular biology, the evaluating the underlying causes of this severe pathology are still bleak. In this review we have attempted to provide a landscape of the underlying mechanisms of cerebral palsy. We have partitioned this review broadly into genetic and proteomic-based studies, which have enriched our understanding about the pathogenesis of CP.
keywords:

cerebral palsy, neuropathology, disease

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