Vesicular lichen nitidus

Shangqing Lin; Xiaohui Wang; Mengjie Lin; Jun Ren

doi:10.5114/ada.2022.117562

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Letter to the Editor

Vesicular lichen nitidus

Shangqing Lin

¹

,

Xiaohui Wang

¹

,

Mengjie Lin

²

,

Jun Ren

¹

Department of Dermatology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen, China
Department of Pathology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen, Chin

Adv Dermatol Allergol 2022; XXXIX (3): 640-641

DOI: https://doi.org/10.5114/ada.2022.117562

Online publish date: 2022/07/14

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A 33-year-old man was presented with flat-topped lesions distributed over the limbs and trunk accompanied with occasional pruritus for nearly 8 years. No other cutaneous or mucous lesions were detected. He denied any significant medical problems or family history. On examination, there were discrete, grouped, flesh-coloured, flat-topped papules or vesicles measuring 1 to 2 mm in diameter distributed over the limbs and lower abdomen (Figure 1 A). Histopathological examination showed the focal degeneration of the basal layer with obvious separation of epidermis immediately beneath well-circumscribed lymphohistiocytic cells infiltrating like “ball-in-claw” rete ridges (Figure 1 B). To further determine the histologic origin of vesicles, immunohistochemistry of CD31/CD34 (blood vessel marker) and D2-40 (lymphatic vessel marker) was performed. But no positive staining of vesicles was found (Figures 1 C, D). Based on clinical and histopathological findings, we further confirmed the final diagnosis of vesicular lichen nitidus (VLN). However, the lesions were hardly improved after topical corticosteroids.

Vesicular lichen nitidus

Shangqing Lin 1 , Xiaohui Wang 1 , Mengjie Lin 2 , Jun Ren 1

Shangqing Lin

¹

,

Xiaohui Wang

¹

,

Mengjie Lin

²

,

Jun Ren

¹