Visualization of synaptic vesicle dynamics with fluorescence proteins

Wang Li; Chunyang Geng; Bo Liu

doi:10.5114/fn.2018.74656

eISSN: 1509-572x
ISSN: 1641-4640

Folia Neuropathologica

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

1/2018
vol. 56

Send email

Copy url:

abstract:

Review paper

Visualization of synaptic vesicle dynamics with fluorescence proteins

Wang Li

,

Chunyang Geng

,

Bo Liu

Folia Neuropathol 2018; 56 (1): 21-29

DOI: https://doi.org/10.5114/fn.2018.74656

Online publish date: 2018/03/28

View full text Get citation

PlumX metrics:

Synaptic vesicle (SV) will be transported to the bouton along the axon, once it is formed in a cell body. After docking in the active zone, neurotransmitters will be released upon the stimulation, and then transmission of chemical signals will be initiated. Presently, many advanced technologies and burgeoning molecular sensors are being used to explore the synaptic transmission. These studies provide a new sight into the presynaptic structure and its function. The present review summarizes the application of fluorescent proteins (FPs) for SV tracking and recycling. Some FPs and relevant imaging technologies such as fluorescence resonance energy transfer (FRET), fluorescence recovery after photobleaching (FRAP) and fluorescence lifetime imaging microscopy (FLIM), are introduced here. In addition, some examples are also analyzed to visualize the dynamics of SVs in living cells with the help of some FPs.

keywords:

Visualization of synaptic vesicle dynamics with fluorescence proteins

Wang Li , Chunyang Geng , Bo Liu

synaptic vesicle, fluorescent proteins, fluorescent technologies, dynamics

Wang Li

,

Chunyang Geng

,

Bo Liu