What do we know about gastrointestinal tract development in intrauterine growth retarded neonates?

Michał Mickiewicz; Piotr Pietrzak; Anna Kotunia; Cornelia C. Metges; Paul Guilloteau; Romuald Zabielski

doi:10.5114/pg.2010.13942

eISSN: 1897-4317
ISSN: 1895-5770

Gastroenterology Review/Przegląd Gastroenterologiczny

Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

1/2010
vol. 5

Send email

Copy url:

abstract:

Review paper

What do we know about gastrointestinal tract development in intrauterine growth retarded neonates?

Michał Mickiewicz

,

Piotr Pietrzak

,

Anna Kotunia

,

Cornelia C. Metges

,

Paul Guilloteau

,

Romuald Zabielski

Przegląd Gastroenterologiczny 2010; 5 (1): 8–14

DOI: https://doi.org/10.5114/pg.2010.13942

Online publish date: 2010/05/07

View full text Get citation

PlumX metrics:

Intrauterine growth retardation (IUGR) is a worldwide problem. In Poland 6% children every year are given birth with IUGR symptoms. In order to classify offspring as IUGR, three conditions must be fulfilled: low birth weight, fast compensation for weight loss, and in consequence excessive fat content in the body. There are many papers about connection between IUGR and development of so called civilization diseases in adults. Different protein level content and incorrect energetic balance of the diet of pregnant mothers is considered a main reason of IUGR. Surprisingly, there is nearly no data on gastrointestinal tract development in IUGR newborns. Our preliminary data suggest that in IUGR fetuses the gastrointestinal tract development is different from that in normal fetuses leading to disturbances in e.g. closing intestinal barrier and absorption which might explain further health disturbances. Better understanding of these processes will help to elaborate nutrition programs that will reduce the consequences of IUGR.

keywords:

What do we know about gastrointestinal tract development in intrauterine growth retarded neonates?

Michał Mickiewicz , Piotr Pietrzak , Anna Kotunia , Cornelia C. Metges , Paul Guilloteau , Romuald Zabielski

intrauterine growth retardation, gastrointestinal tract, maturation, neonatal pigs

Michał Mickiewicz

,

Piotr Pietrzak

,

Anna Kotunia

,

Cornelia C. Metges

,

Paul Guilloteau

,

Romuald Zabielski