Tissue expression of IGF-1 protein in patient with CRC (adenocarcinoma, G2). ABC method. Hemotoxylin counterstained. Objective magn. 40×
Expression of various insulin-like growth factor-1 mRNA isoforms in colorectal cancer
Autor: Marzena Demska
Data: 11.07.2012
Kategorie:
Pierś
Przewód pokarmowy
Mięsaki tkanek miękkich, kości i GIST
Układ moczowo-płciowego
Gruczoły wydzielania wewnętrznego
Płuco i opłucna
Inne
Narządy głowy i szyi
Ginekologia onkologiczna
Czerniak
Gruczoł krokowy
Terapia wspomagająca
Działy:
Doniesienia naukowe
Aktualności Several epidemiological studies have attempted to demonstrate a relationship between increased serum level of insulin-like growth factor 1 (IGF-1) and an augmented risk of developing colorectal cancers (CRC). The human IGF-1 gene is composed of 6 exons and demonstrated expression of 6 different splice variants (isoforms) of mRNA (IA, IB, IC, IIA, IIB and IIC).The aim of the study was to evaluate the expression of different isoforms of IGF-1 mRNA in CRC and normal colon tissue.
