Constipation – a difficult therapeutic problem

Tomasz Dzierżanowski; Grażyna Rydzewska

doi:10.5114/pg.2012.32063

eISSN: 1897-4317
ISSN: 1895-5770

Gastroenterology Review/Przegląd Gastroenterologiczny

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5/2012
vol. 7

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abstract:

Review paper

Constipation – a difficult therapeutic problem

Tomasz Dzierżanowski

,

Grażyna Rydzewska

Prz Gastroenterol 2012; 7 (5): 249–263

DOI: https://doi.org/10.5114/pg.2012.32063

Online publish date: 2012/11/28

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Constipation as a disorder of heterogeneous etiology is a common and often refractory clinical problem. Treatment of chronic constipation depends on the pathophysiological types that often overlap each other. Secondary constipation is brought about by many coinciding causes, so the diagnostics and therapy should be multifactorial against risk factors, dietary, behavioral and care errors. Patients with advanced, progressive illness are particularly exposed to persistent constipation, especially those taking opioid analgesics. In these patients diagnostics is more difficult and therapy usually ineffective, so the emphasis is put on prevention by keeping to appropriate diet and nursing. A novel method for prophylaxis and managing constipation in patients requiring opioid therapy is treatment with combined preparations consisting of an opioid agent and an opioid antagonist.

keywords:

Constipation – a difficult therapeutic problem

Tomasz Dzierżanowski , Grażyna Rydzewska

constipation, palliative care, opioids

Tomasz Dzierżanowski

,

Grażyna Rydzewska