Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report

Joanna Bacharewicz-Szczerbicka; Teresa Reduta; Paulina Kiluk; Anna Andrzejewska; Iwona Flisiak

doi:10.5114/dr.2015.53420

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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4/2015
vol. 102

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abstract:

Original paper

Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report

Joanna Bacharewicz-Szczerbicka

,

Teresa Reduta

,

Paulina Kiluk

,

Anna Andrzejewska

,

Iwona Flisiak

Przegl Dermatol 2015, 102, 322–325

DOI: https://doi.org/10.5114/dr.2015.53420

Online publish date: 2015/09/22

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AMA

Bacharewicz-Szczerbicka J, Reduta T, Kiluk P, Andrzejewska A, Flisiak I. Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report. Dermatology Review/Przegląd Dermatologiczny. 2015;102(4):322-325. doi:10.5114/dr.2015.53420.

APA

Bacharewicz-Szczerbicka, J., Reduta, T., Kiluk, P., Andrzejewska, A.,  & Flisiak, I. (2015). Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report. Dermatology Review/Przegląd Dermatologiczny, 102(4), 322-325. https://doi.org/10.5114/dr.2015.53420

Chicago

Bacharewicz-Szczerbicka, Joanna, Teresa Reduta, Paulina Kiluk, Anna Andrzejewska,  and Iwona Flisiak. 2015. "Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report". Dermatology Review/Przegląd Dermatologiczny 102 (4): 322-325. doi:10.5114/dr.2015.53420.

Harvard

Bacharewicz-Szczerbicka, J., Reduta, T., Kiluk, P., Andrzejewska, A.,  and Flisiak, I. (2015). Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report. Dermatology Review/Przegląd Dermatologiczny, 102(4), pp.322-325. https://doi.org/10.5114/dr.2015.53420

MLA

Bacharewicz-Szczerbicka, Joanna et al. "Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report." Dermatology Review/Przegląd Dermatologiczny, vol. 102, no. 4, 2015, pp. 322-325. doi:10.5114/dr.2015.53420.

Vancouver

Bacharewicz-Szczerbicka J, Reduta T, Kiluk P, Andrzejewska A, Flisiak I. Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report. Dermatology Review/Przegląd Dermatologiczny. 2015;102(4):322-325. doi:10.5114/dr.2015.53420.

PlumX metrics:

Introduction. Generalized granuloma annulare (GGA) is characterized by a chronic course and a poor response to treatment. So far cases of GGA coexisting with diabetes, hyperlipidemia, thyroid diseases and malignant neoplasms have been described.

Objective. To present a case of generalized granuloma annulare coexisting with metastatic carcinoma of unknown primary localization.

Case report. A 58-year-old patient was diagnosed with metastases to lymph nodes of squamous cell carcinoma of unknown primary localization in June 2014. The patient was admitted in November 2014 due to skin lesions lasting since April 2014. On examination, disseminated, red papules with annular distribution on the neck, trunk and upper limbs were noticed. The lymph nodes were enlarged. The histopathological examination of papular lesions revealed granuloma annulare. After skin biopsy the flattening of those lesions was observed.

Conclusions. The presented case indicates the need of diagnostic examinations for cancer in patients with GGA.

keywords:

Generalized granuloma annulare coexisting with metastatic carcinoma of unknown origin (CUP syndrome) – a case report

Joanna Bacharewicz-Szczerbicka , Teresa Reduta , Paulina Kiluk , Anna Andrzejewska , Iwona Flisiak

treatment, coexistence, generalized granuloma annulare, trigger factors, CUP syndrome

Joanna Bacharewicz-Szczerbicka

,

Teresa Reduta

,

Paulina Kiluk

,

Anna Andrzejewska

,

Iwona Flisiak