Original paper<br>SAPHO syndrome – heterogeneity of clinical course – diagnostic problems

Agnieszka Zielińska; Robert Rupiński; Anna Filipowicz-Sosnowska

eISSN: 2084-9834
ISSN: 0034-6233

Reumatologia/Rheumatology

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4/2006
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abstract:

Original paper
SAPHO syndrome – heterogeneity of clinical course – diagnostic problems

Agnieszka Zielińska

,

Robert Rupiński

,

Anna Filipowicz-Sosnowska

RU 2006; 44, 4: 213-219

Online publish date: 2006/09/04

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SAPHO syndrome is a heterogeneous disorder that involves bone, joints with multifocal location, skin and organs. The most frequent forms of bone and joint involvement are: anterior wall pain, spine pain and swelling of sterno-clavicular joints. The most frequent forms of skin involvement are palmo-plantar pustulosis and acne, although a lack of skin involvement does not preclude disease diagnosis. The disease course varies between patients from mild forms to severe. The article presents differences in clinical manifestation and disease course in 9 observed patients. Laboratory and radiological results and therapeutic possibilities are discussed.

keywords:

SAPHO, pustulosis palmo-plantaris, acne,osteitis, hyperostosis

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Original paperSAPHO syndrome – heterogeneity of clinical course – diagnostic problems

Agnieszka Zielińska , Robert Rupiński , Anna Filipowicz-Sosnowska

SAPHO, pustulosis palmo-plantaris, acne,osteitis, hyperostosis

Original paper
SAPHO syndrome – heterogeneity of clinical course – diagnostic problems

Agnieszka Zielińska

,

Robert Rupiński

,

Anna Filipowicz-Sosnowska