eISSN: 2084-9885
ISSN: 1896-6764
Neuropsychiatria i Neuropsychologia/Neuropsychiatry and Neuropsychology
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4/2016
vol. 11
 
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abstract:
Case report

Psychotic depression as an initial symptom of Huntington’s disease – a case report

Joanna Salagierska
,
Agnieszka Remlinger-Molenda
,
Daniel Zielonka
,
Janusz Rybakowski

Neuropsychiatria i Neuropsychologia 2016; 11, 4: 148–151
DOI: https://doi.org/10.5114/nan.2016.65646
Online publish date: 2017/02/08
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Huntington’s disease (HD) is a progressive neurodegenerative disorder which is caused by mutation of the HTT gene on chromosome 4. The characteristic triad of HD includes motor disturbances, cognitive impairment and psychiatric symptoms. The article presents the case of a female patient, 47 years old, with an episode of psychotic depression as an initial symptom of HD, hospitalized at the Department of Adult Psychiatry, Poznan University of Medical Sciences. A supposition of HD was made on the basis of drug-resistant depression, occurrence of neurological symptoms and the family history of HD. The diagnosis of HD was confirmed by genetic testing. Intensive treatment with antidepressants brought about a favorable therapeutic effect and the patient was discharged to continue her treatment in the outpatient clinic for HD.
keywords:

Huntington’s disease, depression
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