Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia

Urszula Maińska; Martyna Sławińska; Wojciech Baran; Wojciech Biernat; Aleksandra Sejda; Roman Nowicki; Michał Sobjanek

doi:10.5114/dr.2022.126604

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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6/2022
vol. 109

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abstract:

Case report

Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia

Urszula Maińska

¹

,

Martyna Sławińska

²

,

Wojciech Baran

³

,

Wojciech Biernat

⁴

,

Aleksandra Sejda

⁵

,

Roman J. Nowicki

²

,

Michał Sobjanek

²

Dermatology Student Scientific Association at the Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland; Dermatologiczne Studenckie Koło Naukowe przy Katedrze i Klinice Dermatologii, Wenerologii i Alergologii, Wydział Lekarski, Gdański Uniwersytet Medyczny, Gdańsk, Polska
Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland; Katedra i Klinika Dermatologii, Wenerologii i Alergologii, Wydział Lekarski, Gdański Uniwersytet Medyczny, Gdańsk, Polska
Department of Hematology and Transplantology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland; Katedra i Klinika Hematologii i Transplantologii, Wydział Lekarski, Gdański Uniwersytet Medyczny, Gdańsk, Polska
Department of Pathomorphology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland; Katedra i Zakład Patomorfologii, Wydział Lekarski, Gdański Uniwersytet Medyczny, Gdańsk, Polska
Department of Pathomorphology and Forensics, Collegium Medicum, Medical Faculty, Warmia and Mazury University, Olsztyn, Poland; Katedra Patomorfologii i Medycyny Sądowej, Collegium Medicum, Wydział Lekarski, Uniwersytet Warmińsko-Mazurski, Olsztyn, Polska

Dermatol Rev/Przegl Dermatol 2022, 109, 453-459

DOI: https://doi.org/10.5114/dr.2022.126604

Online publish date: 2023/04/21

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AMA

Maińska U, Sławińska M, Baran W, et al. Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia. Dermatology Review/Przegląd Dermatologiczny. 2022;109(6):453-459. doi:10.5114/dr.2022.126604.

APA

Maińska, U., Sławińska, M., Baran, W., Biernat, W., Sejda, A.,  & Nowicki, R. J. et al. (2022). Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia. Dermatology Review/Przegląd Dermatologiczny, 109(6), 453-459. https://doi.org/10.5114/dr.2022.126604

Chicago

Maińska, Urszula, Martyna Sławińska, Wojciech Baran, Wojciech Biernat, Aleksandra Sejda, Roman J Nowicki,  and Michał Sobjanek. 2022. "Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia". Dermatology Review/Przegląd Dermatologiczny 109 (6): 453-459. doi:10.5114/dr.2022.126604.

Harvard

Maińska, U., Sławińska, M., Baran, W., Biernat, W., Sejda, A., Nowicki, R.,  and Sobjanek, M. (2022). Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia. Dermatology Review/Przegląd Dermatologiczny, 109(6), pp.453-459. https://doi.org/10.5114/dr.2022.126604

MLA

Maińska, Urszula et al. "Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia." Dermatology Review/Przegląd Dermatologiczny, vol. 109, no. 6, 2022, pp. 453-459. doi:10.5114/dr.2022.126604.

Vancouver

Maińska U, Sławińska M, Baran W, Biernat W, Sejda A, Nowicki R et al. Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia. Dermatology Review/Przegląd Dermatologiczny. 2022;109(6):453-459. doi:10.5114/dr.2022.126604.

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Introduction:
Xanthogranuloma necrobioticum is a rare, chronic granulomatous disease manifested by the presence of papules and yellowish nodules, most often located in the orbital area. Because of its rarity, the diagnosis and treatment of this dermatosis may be difficult, therefore, the authors found presentation of a case purposeful.

Case report:
A case of a 57-year-old male with xanthogranuloma necrobioticum coexisting with monoclonal gammopathy of undetermined significance and neutropenia of undetermined etiology is presented.

Conclusions:
Patients diagnosed with xanthogranuloma necrobioticum should be under long-term observation considering the possibility of co-occurrence of a hematological disease. Achieving therapeutic efficacy may be difficult and requires a complex therapeutic strategy.

keywords:

Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia

Urszula Maińska 1 , Martyna Sławińska 2 , Wojciech Baran 3 , Wojciech Biernat 4 , Aleksandra Sejda 5 , Roman J. Nowicki 2 , Michał Sobjanek 2

xanthogranuloma necrobioticum, monoclonal gammopathy, neutropenia, triamcinolone acetate, intravenous immunoglobulin preparations

Urszula Maińska

¹

,

Martyna Sławińska

²

,

Wojciech Baran

³

,

Wojciech Biernat

⁴

,

Aleksandra Sejda

⁵

,

Roman J. Nowicki

²

,

Michał Sobjanek

²